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AliasServer Florian Iragne, Aurélien Barré, Nicolas Goffard, Antoine de Daruvar AliasServer: a web server to handle multiple aliases used to refer to proteins. The variety of identifiers used to refer to
the same biological object, such as a protein, is a recurrent source of
problems. When different aliases are used for the same protein, bringing
together data or data sets requires a substantial amount of time and
effort. Aliases have various origins: systematic names defined by
sequencing projects, accession numbers used by public database, protein
names used by the biologists, etc. While the designation of a
universally-accepted unique identifier would theoretically solve the
problem, this has absolutely no chance of happening given the
multiplication and growth of molecular biology databases. Therefore,
solutions must be proposed to help in the handling of the diversity of
aliases. In this respect, species oriented databases like SGD (Cherry et
al., 1998) for Saccharomyces cerevisiae, that collect and centralize
aliases, are very helpful. However, the help provided by such resources is
limited for different reasons: they are specialized to a given species,
they are not designed to easily incorporate new alias definitions, and
they do not offer to users and programs dedicated "alias management
services" such as the translation of identifiers from one type to
another, like systematic names into accession numbers. We developed
AliasServer in an attempt to overcome these limits,. Our system is
designed to load and store aliases attached to the proteomes of an
extendable list of organisms and to provide services through both an
interactive web interface and a SOAP based API (Box et al., 2000).
Version Imprimable - Printable Version
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